Molecular angiogenesis
نویسندگان
چکیده
منابع مشابه
Molecular Imaging of Tumor Angiogenesis
Molecular imaging has recently been defined by the Society of Nuclear Medicine as ‘the visualization, characterization, and measurement of biological processes at the molecular and cellular levels in humans and other living systems’ (Mankoff 2007). It usually exploits specific labeled molecular probes, as well as intrinsic tissue characteristics as the source of image contrast, and uses a numbe...
متن کاملMolecular Mechanisms of Tumor Angiogenesis
It is well established that progression from a pre-malignant to malignant invasive tumor phenotype is dependent on angiogenesis1-7. As such, a hallmark of all solid cancers is their ability to induce the formation of their own blood supply thereby sustaining their growth and is characterized by increases in endothelial cell (EC) proliferation and blood vessel heterogeneity8-10. The ‘angiogenic ...
متن کاملAngiogenesis Dysregulation in Psoriatic Arthritis: Molecular Mechanisms
There is evidence that psoriatic arthritis is closely linked to angiogenesis. Morphological changes described in blood vessels of psoriatic arthritis joints suggest the presence of a dysregulated angiogenesis resulting in the formation of immature vessels. Even if the reason of this inefficient angiogenesis is still unclear, an imbalance between angiogenic and antiangiogenic factors is probably...
متن کاملMR molecular imaging of aortic angiogenesis.
OBJECTIVES The objectives of this study were to use magnetic resonance (MR) molecular imaging to 1) characterize the aortic neovascular development in a rat model of atherosclerosis and 2) monitor the effects of an appetite suppressant on vascular angiogenesis progression. BACKGROUND The James C. Russell:LA corpulent rat strain (JCR:LA-cp) is a model of metabolic syndrome characterized by obe...
متن کاملMolecular Basis of Angiogenesis in Ovarian Cancer
Epithelial ovarian cancer (EOC) is the most common malignancy of the female genital tract in Western countries: 1–2% of all women develop EOC at some time during their lives. Most women with EOC present with peritoneal spread, the principal cause of morbidity and mortality. Owing to the paucity of symptoms and their insidious onset, most patients present with advanced disease, and five year sur...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 1999
ISSN: 1074-5521
DOI: 10.1016/s1074-5521(99)80081-7